Main Street Inn B&B

Sainte Genevieve, Missouri

Main Street Inn B&B

Sainte Genevieve, Missouri

Main Street Inn B&B

Sainte Genevieve, Missouri

Main Street Inn B&B

Sainte Genevieve, Missouri

A Historic Bed & Breakfast Built in 1882

Originally built in 1882, as the Meyer Hotel, the Main Street Inn B&B has long been considered one of Missouri’s finest bed and breakfast establishments.

Having recently undergone an extensive year-long renovation, Proprietors, Susan O’Donnell and Patrick Fahey, along with Innkeeper, Jean Marie Rozier Sellberg, are thrilled to re-open the Main Street Inn B&B and welcome our guests to what we hope will be a truly wonderful experience.

Located in the heart of Sainte Genevieve’s Historic District, and surrounded by beautiful wine country, we are just a short one-hour drive from both St. Louis and Cape Girardeau, five hours from Chicago and just a little over four hours from Nashville.

 If you are looking for a relaxing and peaceful getaway, the Main Street Inn B&B is the perfect destination.

Room Rate Specials

Coming Soon!

On Going Specials
North Parlor Game Room
North Parlor North Parlor Dining Room 2nd Floor Porch

FOR OUR GUESTS

A full Breakfast is served every morning between 9:00am and 10:30am, with early morning coffee available on all three floors by 7:00am, for the early risers.

Each evening of your stay, you are invited to attend a simple wine reception from 6:00pm to 7:00pm in the North Parlor.


  

 

Our Rooms

How to Find Us

221 North Main Street, Sainte Genevieve, Missouri 63670


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Guest Reviews

We strive to provide an exceptional level of service for every guest, and are proud to have a 4.5-star rating on TripAdvisor.

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